Levosimendan mechanism | 動物用藥查詢網
,由MSNieminen著作·2013·被引用188次—Theprincipalpharmacologicaleffectsoflevosimendanare(a)increasedcardiaccontractilitybycalciumsensitisationoftroponinC,(b)vasodilation,and(c) ...,LevosimendanincreasescalciumsensitivitytomyocytesbybindingtotroponinCinacalciumdependentmanner.Thisincreasescontractilitywithoutraising ...,Overallthedrughasatwofoldmechanismofaction.ItleadstogreaterionotrophybyincreasingthecalciumsensitivityasitbindstoTroponinandthis ...,由EPashkovetsky著作·2019·被引用12次—Levosima...
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A review of levosimendan in the treatment of heart failure | 動物用藥查詢網
Levosimendan: current data | 動物用藥查詢網
由 MS Nieminen 著作 · 2013 · 被引用 188 次 — The principal pharmacological effects of levosimendan are (a) increased cardiac contractility by calcium sensitisation of troponin C, (b) vasodilation, and (c) ... Read More
Levosimendan: Uses | 動物用藥查詢網
Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising ... Read More
Levosimendan | 動物用藥查詢網
Overall the drug has a two fold mechanism of action. It leads to greater ionotrophy by increasing the calcium sensitivity as it binds to Troponin and this ... Read More
Use of levosimendan in acute and advanced heart failure | 動物用藥查詢網
由 E Pashkovetsky 著作 · 2019 · 被引用 12 次 — Levosimanden: mechanism of action ... Levosimendan is an inotropic drug that has three major mechanisms of action: positive inotropy, vasodilation ... Read More
Levosimendan | 動物用藥查詢網
由 Z Papp 著作 · 2012 · 被引用 328 次 — Interpretation of the complex mechanism of levosimendan action requires that all potential pharmacological interactions are analyzed carefully ... Read More
Pharmacology of levosimendan | 動物用藥查詢網
由 A Pathak 著作 · 2013 · 被引用 139 次 — The main mechanism of action described for this drug is an increase in the troponin C affinity for Ca2+ and a stabilization of the troponin C ... Read More
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