Kanamycin | 動物用藥查詢網
![Kanamycin](https://i.imgur.com/TbfVXFL.jpg)
2010年4月12日—Workingconcentrationis50μg/ml,or25μg/mlforlow-copyplasmidslikePACs.Stocksolutionis35mg/mlinwater(kanamycinisinsoluble ...
![Kanamycin](https://i.imgur.com/TbfVXFL.jpg)
Bacteriocidal. Diffuses through the porinchannels in the outer membrane of gram-negative bacteria. Interacts with at least three ribosomal proteins, inhibiting protein synthesis and increasing translation errors.
Mechanism of ResistanceKanamycin is inactivated by bacterial aminophosphotransferases (APHs). The APHs inactivate kanamycin by transferring the γ-phosphate of ATP to the hydroxyl group in the 3 position of the pseudosaccharide. The KanR gene codes for kanamycin resistance. Several versions of this gene exist, with varying crossover resistance to other antibiotics such as neomycin[1] or gentamycin[2].
Working Concentration and Stock SolutionWorking concentration is 50 μg/ml, or 25 μg/ml for low-copy plasmids like PACs[3]. Stock solution is 35 mg/ml in water (kanamycin ...
19 Common Questions About Kanamycin | 動物用藥查詢網
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Kanamycin | 動物用藥查詢網
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Working concentration (dilution) of kanamycin | 動物用藥查詢網
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