Methacholine | 動物用藥查詢網
![Methacholine](https://i.imgur.com/TbfVXFL.jpg)
Methacholine(INN,USAN)(tradenameProvocholine),alsoknownasAcetyl-β-methylcholine,isasyntheticcholineesterthatactsasanon-selective ...
![Methacholine](https://i.imgur.com/TbfVXFL.jpg)
From Wikipedia, the free encyclopedia
Chemical compound
Methacholine (INN, USAN) (trade name Provocholine), also known as acetyl-β-methylcholine, is a synthetic choline ester that acts as a non-selective muscarinic receptor agonist in the parasympathetic nervous system.
Medical uses[edit]Methacholine is primarily used to diagnose bronchial hyperreactivity,[1] which is the hallmark of asthma and also occurs in chronic obstructive pulmonary disease. This is accomplished through the bronchial challenge test, or methacholine challenge, in which a subject inhales aerosolized methacholine, leading to bronchoconstriction. Other therapeutic uses are limited by its adverse cardiovascular effects, such as bradycardia and hypotension, which arise from its function as a cholinomimetic.
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