Methacholine: Uses | 動物用藥查詢網
![Methacholine: Uses](https://i.imgur.com/TbfVXFL.jpg)
Methacholineisaparasympathomimeticbronchoconstrictorusedtodiagnosebronchialhyperreactivityinsubjectswhodonothaveclinicallyapparentasthma.
![Methacholine: Uses](https://i.imgur.com/TbfVXFL.jpg)
Methacholine is a non-specific cholinergic agonist (parasympathomimetic) that acts through muscarinic receptors in the lungs to induce bronchoconstriction, which is more significant in patients with asthma than those without. Therefore, methacholine carries a risk of severe bronchoconstriction, especially in patients with pre-existing reduced pulmonary function (typically baseline FEV1 < 60% or < 1.5 L, at least in adults), clinically apparent asthma or wheezing, or other health conditions such as uncontrolled hypertension, aortic aneurysm, or history of myocardial infarction or stroke. Use in patients with epilepsy, vagotonia, peptic ulcer disease, thyroid disease, urinary tract obstruction or other conditions that could be adversely affected by a cholinergic agent is not recommended. Also, there is a potential risk to healthcare workers administering the methacholine challenge test; proper precautions and pr...
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![](https://i.imgur.com/TbfVXFL.jpg)
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